Fluorescent Fusion Proteins
Genetically
encoded fluorescent fusion proteins provide specific
labeling of sub-cellular compartments in living mammalian
cells. In addition, they can often be used as reporters
that reveal - in real time - cell signaling, changes in
expression, or alteration of endogenous genes.
Reporters for Cre
Recombinase
The
activation of Cre recombinase is necessary for genetic
recombination. The Stoplight Reporter changes color in the
presence of Cre recombinase and provides a clear indication
of genetic recombination within a cell.
G Protein Marker
This
marker for G protein and GPCR activation is fully
functional and characterized. It leaves the membrane of the
cell when signaling occurs.
GFP Biosensors for HTS
Genetically
encoded fluorescent biosensors have impact both as tools
for basic research and as readouts in cell-based
high-throughput assays. Our biosensors are built using a
proprietary complementation technology that works in
mammalian cells. This validated approach to screening and
analysis offers significant per well cost reduction and
improved sensitivity compared to fluorescent dye assays.